Morphological properties

This sub-section examines the consistency of morphometric properties of 3D reconstructed morphologies in the reconstructed microcircuit against relevant literature.

Evaluated properties include Sholl statistics, dendritic and axonal lengths, dendritic and axonal extents, soma diameters, dendritic and axonal segment branch order and path distance statistics.

The results of the consistency check were categorized as input, consistent, possibly consistent, inconsistentnot implemented or not applicable based on agreement with a given evaluation criterion.

paper(s)
paper(s)
paper(s)
paper(s)
paper(s)

consistent - Medini, P. - Cell-type–specific sub- and suprathreshold receptive fields of layer 4 and layer 2/3 pyramids in rat primary visual cortex ext_link

input/validation/consistent
consistent
evaluation criterion
Dendritic length of L4 and L2/3PCs
id
1
species
rat
age
adult
brain region
primary visual cortex
layer
2,3
cell
pc
aspect
Connectivity of cortical pyramidal neurons
statement
L4Ps may receive mostly thalamic inputs, whereas L2/3Ps may receive both thalamic and cortical inputs from layer 4
pmid
21704132
title
Cell-type–specific sub- and suprathreshold receptive fields of layer 4 and layer 2/3 pyramids in rat primary visual cortex
contact Name
Medini, P.
contributed by
John Fielden
JWG notes
checked by
SR

consistent - Joachim Luebke - Columnar Organization of Dendrites and Axons of Single and Synaptically Coupled Excitatory Spiny Neurons in Layer 4 of the Rat Barrel Cortex ext_link

input/validation/consistent
consistent
evaluation criterion
Dendritic morphometrics of L4 spiny cells
id
2
species
rat
age
brain region
barrel cortex
layer
cell
spiny stellate, pyramidal cell
aspect
describe the morphology of two classes of synaptically coupled excitatory neurons in layer 4
statement
Spiny stella and star pyramidal neurons of layer 4 serve to amplify thalamic input and relay excitation verically within a single cortical column
pmid
10884314
title
Columnar Organization of Dendrites and Axons of Single and Synaptically Coupled Excitatory Spiny Neurons in Layer 4 of the Rat Barrel Cortex
contact Name
Joachim Luebke
contributed by
Guy Atenekeng
JWG notes
Data!
checked by
SR

consistent - j.f. Staiger - Functional Diversity of Layer IV spiny neurons in rat somatosensory cortex: quantitative morphology of electrophysiologically characterized and biocytin labeled cells ext_link

input/validation/consistent
consistent
evaluation criterion
Morphometrics of L4 excitatory cells
id
3
species
rat
age
p19-21
brain region
somatosensory cortex
layer
L4 & L2/3
cell
spiny neurons
aspect
detailed morphological data charaterizing 3 subpopulations of spiny cells
statement
58% spiny stellate cells, 25% star pyramidal cells, 17 % pyramidal cells
pmid
15054049
title
Functional Diversity of Layer IV spiny neurons in rat somatosensory cortex: quantitative morphology of electrophysiologically characterized and biocytin labeled cells
contact Name
j.f. Staiger
contributed by
Sarah Strauss
JWG notes
Data!
checked by
SR

consistent - Staiger, Jochen F. - Functional Diversity of Layer IV Spiny Neurons in Rat Somatosensory Cortex: Quantitative Morphology of Electrophysiologically Characterized and Biocytin Labeled Cells ext_link

input/validation/consistent
consistent
evaluation criterion
Morphometrics of L4 excitatory cells
id
4
species
rat
age
brain region
Somatosensory Cortex
layer
L4
cell
PC,SS
aspect
Morphology of Electrophysiologically Characterized
statement
morphological data characterizing three subpopulations of spiny neurons in slices of adolescent rats: (i) spiny stellate cells (58%), (ii) star pyramidal cells (25%) and (iii) pyramidal cells (17%), which can be distinguished objectively by the preferential orientation of their dendritic stems
pmid
15054049
title
Functional Diversity of Layer IV Spiny Neurons in Rat Somatosensory Cortex: Quantitative Morphology of Electrophysiologically Characterized and Biocytin Labeled Cells
contact Name
Staiger, Jochen F.
contributed by
Y. Shi
JWG notes
Data!
checked by
SR

consistent - Martin Deschenes - Intracortical axonal projections of lamina VI cells of the primary somatosensory cortex in the rat: a single-cell labeling study. ext_link

input/validation/consistent
consistent
evaluation criterion
L6 morphological diversity - axonal projections of PCs and GABAergic interneurons
id
5
species
rat
age
adult
brain region
S1
layer
6a
cell
neurons
aspect
cell labelling and projections
statement
different types of layer 6 projecting neurons
pmid
9236245
title
Intracortical axonal projections of lamina VI cells of the primary somatosensory cortex in the rat: a single-cell labeling study.
contact Name
Martin Deschenes
contributed by
J-P
JWG notes
checked by
SR

consistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability ext_link

input/validation/consistent
consistent
evaluation criterion
L2/3 Basket Cell Total Dendritic Length
id
6
species
rat
age
P20-29
brain region
somatosensory cortex
layer
2,3
cell
L2/3 interneurons
aspect
axonal and dendritic morphology, excitability
statement
4 "types of axonal projection patterns" in layer 2/3 (L2/3)
pmid
18802122
title
L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
Rodrigo Perin
JWG notes
Data: rat somatosensory L2/3 INs
checked by
JWG

consistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability ext_link

input/validation/consistent
consistent
evaluation criterion
L2/3 NGC Total Dendritic Length
id
7
species
rat
age
P20-29
brain region
somatosensory cortex
layer
2,3
cell
L2/3 interneurons
aspect
axonal and dendritic morphology, excitability
statement
4 "types of axonal projection patterns" in layer 2/3 (L2/3)
pmid
18802122
title
L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
Rodrigo Perin
JWG notes
Data: rat somatosensory L2/3 INs
checked by
JWG

consistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability ext_link

input/validation/consistent
consistent
evaluation criterion
L2/3 Bitufted Cell Total Axonal Length
id
8
species
rat
age
P20-29
brain region
somatosensory cortex
layer
2,3
cell
L2/3 interneurons
aspect
axonal and dendritic morphology, excitability
statement
4 "types of axonal projection patterns" in layer 2/3 (L2/3)
pmid
18802122
title
L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
Rodrigo Perin
JWG notes
Data: rat somatosensory L2/3 INs
checked by
JWG

consistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability ext_link

input/validation/consistent
consistent
evaluation criterion
L2/3 Bitufted Cell Total Dendritic Length
id
9
species
rat
age
P20-29
brain region
somatosensory cortex
layer
2,3
cell
L2/3 interneurons
aspect
axonal and dendritic morphology, excitability
statement
4 "types of axonal projection patterns" in layer 2/3 (L2/3)
pmid
18802122
title
L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
Rodrigo Perin
JWG notes
Data: rat somatosensory L2/3 INs
checked by
JWG

consistent - Paul L.A. Gabbott, Brian G.M. Dickie, R. Roy Vaid - local circuit neurones in the medial prefrontal cortex (areas 25,32, and 24b) in the rat: Morphology and quantitative distribution ext_link

input/validation/consistent
consistent
evaluation criterion
IN soma size
id
10
species
rat
age
brain region
medial prefrontal cortex
layer
cell
aspect
all kinds of morphology
statement
pmid
9007187
title
local circuit neurones in the medial prefrontal cortex (areas 25,32, and 24b) in the rat: Morphology and quantitative distribution
contact Name
Paul L.A. Gabbott, Brian G.M. Dickie, R. Roy Vaid
contributed by
Sarah Strauss
JWG notes
Data: rat pfc INs
checked by
JWG

consistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - Monosynaptic connections between pairs of L5A pyramidal neurons in columns of juvenile rat somatosensory cortex. ext_link

input/validation/consistent
consistent
evaluation criterion
L5a PC total basal dendritic length
id
11
species
rat
age
18 - 20 days
brain region
somatosensory cortex
layer
L5A
cell
pyramidal neurons
aspect
anatomy and physiology of monosynaptic connections between L5A pyramidal neurons within the barrel columns of somatosensory cortex
statement
existence of monosynaptic connections between slender-tufted L5A pyramidal neurons
pmid
17548800
title
Monosynaptic connections between pairs of L5A pyramidal neurons in columns of juvenile rat somatosensory cortex.
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
Mirjia Herzog
JWG notes
Data: rat P21 somatosensory L5A PCs
checked by
JWG

consistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - Monosynaptic connections between pairs of L5A pyramidal neurons in columns of juvenile rat somatosensory cortex. ext_link

input/validation/consistent
consistent
evaluation criterion
L5a PC total apical dendritic length
id
12
species
rat
age
18 - 20 days
brain region
somatosensory cortex
layer
L5A
cell
pyramidal neurons
aspect
anatomy and physiology of monosynaptic connections between L5A pyramidal neurons within the barrel columns of somatosensory cortex
statement
existence of monosynaptic connections between slender-tufted L5A pyramidal neurons
pmid
17548800
title
Monosynaptic connections between pairs of L5A pyramidal neurons in columns of juvenile rat somatosensory cortex.
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
Mirjia Herzog
JWG notes
Data: rat P21 somatosensory L5A PCs
checked by
JWG

consistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - Monosynaptic connections between pairs of L5A pyramidal neurons in columns of juvenile rat somatosensory cortex. ext_link

input/validation/consistent
consistent
evaluation criterion
L5a PC number basal dendrites
id
13
species
rat
age
18 - 20 days
brain region
somatosensory cortex
layer
L5A
cell
pyramidal neurons
aspect
anatomy and physiology of monosynaptic connections between L5A pyramidal neurons within the barrel columns of somatosensory cortex
statement
existence of monosynaptic connections between slender-tufted L5A pyramidal neurons
pmid
17548800
title
Monosynaptic connections between pairs of L5A pyramidal neurons in columns of juvenile rat somatosensory cortex.
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
Mirjia Herzog
JWG notes
Data: rat P21 somatosensory L5A PCs
checked by
JWG

consistent - Krieger, P. , Kuner, T. and Sakmann B. - Synaptic connections between Layer 5B pyramidal neurons in mouse somatosensory cortex are independent of apical dendrite bundling ext_link

input/validation/consistent
consistent
evaluation criterion
L5 PC basal sholl plot shape
id
14
species
mouse
age
14- 37 d
brain region
somatosensory cortex
layer
L5B
cell
Pyramidal cell
aspect
dendritic arborization and synaptic connection
statement
Dendritic bundling and synaptic input seems independent from each other
pmid
17959790
title
Synaptic connections between Layer 5B pyramidal neurons in mouse somatosensory cortex are independent of apical dendrite bundling
contact Name
Krieger, P. , Kuner, T. and Sakmann B.
contributed by
Yihwa Kim
JWG notes
Data: mouse L5b PCs
checked by
JWG

consistent - Ted L. Petit - The pattern of dendritic development in the cerebral cortex of the rat ext_link

input/validation/consistent
consistent
evaluation criterion
Dendritic morphometrics of TTL5 cells
id
15
species
rats (male)
age
p1-60
brain region
dorsal portion of the sensorimotor Cortex
layer
v
cell
pyramidal
aspect
pattern of dendritic development
statement
several general rules govern the pattern of dendritic differentiation
pmid
3401798
title
The pattern of dendritic development in the cerebral cortex of the rat
contact Name
Ted L. Petit
contributed by
Dimitri Christodoulou
JWG notes
Data!
checked by
SR

consistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - The Relation between Dendritic Geometry, Electrical Excitability, and Axonal Projections of L2/3 Interneurons in Rat Barrel Cortex ext_link

input/validation/consistent
consistent
evaluation criterion
L2/3 IN number of primary dendrites
id
16
species
rat
age
p20-29
brain region
rat barrel cortex
layer
2,3
cell
L2/3 interneurons
aspect
dendritic geometry, electrical excitability and axonal projections
statement
dendritic polarity correlated to intrinsic electrical excitability, axonal projection pattern represents an independent classifier of interneurons
pmid
18787231
title
The Relation between Dendritic Geometry, Electrical Excitability, and Axonal Projections of L2/3 Interneurons in Rat Barrel Cortex
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
John Fielden
JWG notes
Data: rat barrel cortex L2/3 INs
checked by
JWG

consistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - The Relation between Dendritic Geometry, Electrical Excitability, and Axonal Projections of L2/3 Interneurons in Rat Barrel Cortex ext_link

input/validation/consistent
consistent
evaluation criterion
L2/3 IN total dendritic length
id
17
species
rat
age
p20-29
brain region
rat barrel cortex
layer
2,3
cell
L2/3 interneurons
aspect
dendritic geometry, electrical excitability and axonal projections
statement
dendritic polarity correlated to intrinsic electrical excitability, axonal projection pattern represents an independent classifier of interneurons
pmid
18787231
title
The Relation between Dendritic Geometry, Electrical Excitability, and Axonal Projections of L2/3 Interneurons in Rat Barrel Cortex
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
John Fielden
JWG notes
Data: rat barrel cortex L2/3 INs
checked by
JWG

inconsistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability ext_link

input/validation/consistent
inconsistent
evaluation criterion
L2/3 Basket Cell Total Axonal Length
id
18
species
rat
age
P20-29
brain region
somatosensory cortex
layer
2,3
cell
L2/3 interneurons
aspect
axonal and dendritic morphology, excitability
statement
4 "types of axonal projection patterns" in layer 2/3 (L2/3)
pmid
18802122
title
L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
Rodrigo Perin
JWG notes
Data: rat somatosensory L2/3 INs
checked by
JWG

inconsistent - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability ext_link

input/validation/consistent
inconsistent
evaluation criterion
L2/3 NGC Total Axonal Length
id
19
species
rat
age
P20-29
brain region
somatosensory cortex
layer
2,3
cell
L2/3 interneurons
aspect
axonal and dendritic morphology, excitability
statement
4 "types of axonal projection patterns" in layer 2/3 (L2/3)
pmid
18802122
title
L2/3 interneuron groups defined by multiparameter analysis of axonal projection, dendritic geometry, and electrical excitability
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
Rodrigo Perin
JWG notes
Data: rat somatosensory L2/3 INs
checked by
JWG

inconsistent - Yasuhiro R. Tanaka, Yasuyo H. Tanaka, Mitchiteru Konna, Fumino Fujiyama, Takahiro Sonomura, Keiko Okamoto-Futura, Hiroshi Kameda, Hiroyuki Hiori, Takahiro Futura, Kouichi C. Nakamura, and Takeshi Kaneko - Local Connections of Excitatory Neurons to corticothalamic Neurons in the Rat Barrel Cortex ext_link

input/validation/consistent
inconsistent
evaluation criterion
L2/3 PC axon total length
id
20
species
rat
age
brain region
barrel cortex
layer
L2-6
cell
pyramidal neurons
aspect
Connections and some statistics on morphology
statement
corticothalamic neurons strong and focused connections from L4 neurons just above them, and that the most numerous nearby and distant sources of local excitatory connections to corticothalamic neurons were corticothalamic neurons themselves and L6
pmid
22171028
title
Local Connections of Excitatory Neurons to corticothalamic Neurons in the Rat Barrel Cortex
contact Name
Yasuhiro R. Tanaka, Yasuyo H. Tanaka, Mitchiteru Konna, Fumino Fujiyama, Takahiro Sonomura, Keiko Okamoto-Futura, Hiroshi Kameda, Hiroyuki Hiori, Takahiro Futura, Kouichi C. Nakamura, and Takeshi Kaneko
contributed by
Guy Atenekeng
JWG notes
Data: rat barrel cortex PCs
checked by
JWG

inconsistent - Yasuhiro R. Tanaka, Yasuyo H. Tanaka, Mitchiteru Konna, Fumino Fujiyama, Takahiro Sonomura, Keiko Okamoto-Futura, Hiroshi Kameda, Hiroyuki Hiori, Takahiro Futura, Kouichi C. Nakamura, and Takeshi Kaneko - Local Connections of Excitatory Neurons to corticothalamic Neurons in the Rat Barrel Cortex ext_link

input/validation/consistent
inconsistent
evaluation criterion
L4 PC axon total length
id
21
species
rat
age
brain region
barrel cortex
layer
L2-6
cell
pyramidal neurons
aspect
Connections and some statistics on morphology
statement
corticothalamic neurons strong and focused connections from L4 neurons just above them, and that the most numerous nearby and distant sources of local excitatory connections to corticothalamic neurons were corticothalamic neurons themselves and L6
pmid
22171028
title
Local Connections of Excitatory Neurons to corticothalamic Neurons in the Rat Barrel Cortex
contact Name
Yasuhiro R. Tanaka, Yasuyo H. Tanaka, Mitchiteru Konna, Fumino Fujiyama, Takahiro Sonomura, Keiko Okamoto-Futura, Hiroshi Kameda, Hiroyuki Hiori, Takahiro Futura, Kouichi C. Nakamura, and Takeshi Kaneko
contributed by
Guy Atenekeng
JWG notes
Data: rat barrel cortex PCs
checked by
JWG

inconsistent - Yasuhiro R. Tanaka, Yasuyo H. Tanaka, Mitchiteru Konna, Fumino Fujiyama, Takahiro Sonomura, Keiko Okamoto-Futura, Hiroshi Kameda, Hiroyuki Hiori, Takahiro Futura, Kouichi C. Nakamura, and Takeshi Kaneko - Local Connections of Excitatory Neurons to corticothalamic Neurons in the Rat Barrel Cortex ext_link

input/validation/consistent
inconsistent
evaluation criterion
L5 PC axon total length
id
22
species
rat
age
brain region
barrel cortex
layer
L2-6
cell
pyramidal neurons
aspect
Connections and some statistics on morphology
statement
corticothalamic neurons strong and focused connections from L4 neurons just above them, and that the most numerous nearby and distant sources of local excitatory connections to corticothalamic neurons were corticothalamic neurons themselves and L6
pmid
22171028
title
Local Connections of Excitatory Neurons to corticothalamic Neurons in the Rat Barrel Cortex
contact Name
Yasuhiro R. Tanaka, Yasuyo H. Tanaka, Mitchiteru Konna, Fumino Fujiyama, Takahiro Sonomura, Keiko Okamoto-Futura, Hiroshi Kameda, Hiroyuki Hiori, Takahiro Futura, Kouichi C. Nakamura, and Takeshi Kaneko
contributed by
Guy Atenekeng
JWG notes
Data: rat barrel cortex PCs
checked by
JWG

inconsistent - Zhong-Wei Zhang - Maturation of Layer V Pyramidal Neurons in the Rat Prefrontal Cortex: Intrinsic and Synaptic Function ext_link

input/validation/consistent
inconsistent
evaluation criterion
L5 PC total basal dendritic length
id
23
species
rat
age
p3-p21
brain region
prefrontal cortex
layer
L5
cell
pyramidal neurons
aspect
Surface area
statement
approx 629 um² at P3 and 1248um² at P21
pmid
14602839
title
Maturation of Layer V Pyramidal Neurons in the Rat Prefrontal Cortex: Intrinsic and Synaptic Function
contact Name
Zhong-Wei Zhang
contributed by
Guy Atenekeng
JWG notes
Data: rat pfc L5 PCs
checked by
JWG

inconsistent - Zhong-Wei Zhang - Maturation of Layer V Pyramidal Neurons in the Rat Prefrontal Cortex: Intrinsic and Synaptic Function ext_link

input/validation/consistent
inconsistent
evaluation criterion
L5 PC total apical dendritic length
id
24
species
rat
age
p3-p21
brain region
prefrontal cortex
layer
L5
cell
pyramidal neurons
aspect
Surface area
statement
approx 629 um² at P3 and 1248um² at P21
pmid
14602839
title
Maturation of Layer V Pyramidal Neurons in the Rat Prefrontal Cortex: Intrinsic and Synaptic Function
contact Name
Zhong-Wei Zhang
contributed by
Guy Atenekeng
JWG notes
Data: rat pfc L5 PCs
checked by
JWG

inconsistent - Joachim Luebke, Arnd roth, Bert Sakmann - Morphometric Analysis of the columnar innervation domain of neurons connecting Layer 4 and Layer 2/3 of juvenile rat barrel cortex ext_link

input/validation/consistent
inconsistent
evaluation criterion
Axonal and dendritic morphometrics of L2/3 PCs and L4 spiny neurons
id
25
species
rat
age
brain region
barrel cortex
layer
L4 & L2/3
cell
spiny neurons, pyramidal cells
aspect
morphology of connected pairs of cells
statement
investigated the dendritic and axonal morphology of pairs of l4 spiny neurons and l2/3 pyramidal cells
pmid
12967922
title
Morphometric Analysis of the columnar innervation domain of neurons connecting Layer 4 and Layer 2/3 of juvenile rat barrel cortex
contact Name
Joachim Luebke, Arnd roth, Bert Sakmann
contributed by
Sarah Strauss
JWG notes
Data!
checked by
SR

inconsistent - Veronica Egger - Subcolumnar Dendritic and axonal organization of spiny stellate and star pyramidal neurons within a barrel in rat somatosensory cortex ext_link

input/validation/consistent
inconsistent
evaluation criterion
Axonal morphometrics of L4 spiny neurons
id
26
species
rat
age
brain region
barrel cortex
layer
l 4
cell
spiny stellate and star pyramidal neurons
aspect
dendritic symmetry
statement
spiny stellate cells had mostly eccentric morphology, star pyramidal neurons were nearly radially szmmetric
pmid
17656622
title
Subcolumnar Dendritic and axonal organization of spiny stellate and star pyramidal neurons within a barrel in rat somatosensory cortex
contact Name
Veronica Egger
contributed by
Sarah Strauss
JWG notes
Data!
checked by
SR

not applicable - Giogio A. Ascoli - Automated reconstruction of neuronal morphology: An Overview ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
27
species
review
age
review
brain region
layer
cell
aspect
Review on automatic reconstruction
statement
Despite advances in automatic reconstrcution techniques, however, they still have far to go before they surpass manual reconstruction as the methode of choice
pmid
21118703
title
Automated reconstruction of neuronal morphology: An Overview
contact Name
Giogio A. Ascoli
contributed by
Guy Atenekeng
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Susan L. Wearne - Automated reconstruction of three-dimensional neuronal morphology from laser scanning microscopy images. ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
28
species
Mouse and Monkey
age
brain region
Prefrontal cortex
layer
cell
pyramidal
aspect
Show Automatic reconstruction of Layer III but can be apply to other
statement
Provide a much need tool to automated digitization and reconstruction of 3D neuronal morphology that captures detail
pmid
12695107
title
Automated reconstruction of three-dimensional neuronal morphology from laser scanning microscopy images.
contact Name
Susan L. Wearne
contributed by
Guy Atenekeng
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - David Prince - Burst generating and regular spiking layer 5 pyramidal neurons of rat neocortex have different morphological features ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
29
species
rat
age
brain region
neocortex
layer
L5
cell
PC
aspect
morphological features
statement
differences in gross neuronal structure, perhaps even the subtle differences that distinguish subclasses of neurons in a given lamina, are predictive of underlying differences in the type and distribution of ion channels in the nerve cell membrane and connections of cells within the cortical circuit.
pmid
2358553
title
Burst generating and regular spiking layer 5 pyramidal neurons of rat neocortex have different morphological features
contact Name
David Prince
contributed by
Y. Shi
JWG notes
Article unavailable online
checked by
SR

not applicable - Stehen J Smith - Circuit reconstruction tools today ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
30
species
age
brain region
layer
cell
aspect
reconstruction
statement
A review of reconstruction tools
pmid
18082394
title
Circuit reconstruction tools today
contact Name
Stehen J Smith
contributed by
Yihwa Kim
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Alan U. Larkman - Dendritic morphology of pyramidal neurones of the visual cortex of the rat: I. Branching pattern ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
31
species
rat
age
brain region
visual cortex
layer
l2/3, 5
cell
pyramidal neurons
aspect
description of branching patterns of basal and apical dendrites
statement
branching patterns were similar, 3-9 basal trees arose, number of tips in each tree varied widely, path lengths of basal dendrites were constante
pmid
1711057
title
Dendritic morphology of pyramidal neurones of the visual cortex of the rat: I. Branching pattern
contact Name
Alan U. Larkman
contributed by
Sarah Strauss
JWG notes
Article unavailable online
checked by
SR

not applicable - Larkman, Alan U. - Dendritic morphology of pyramidal neurones of the visual cortex of the rat: III. Spine distributions ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
32
species
rat
age
brain region
visual cortex
layer
L23.L5
cell
PC
aspect
Morphology,Spine distributions
statement
pmid
1711059
title
Dendritic morphology of pyramidal neurones of the visual cortex of the rat: III. Spine distributions
contact Name
Larkman, Alan U.
contributed by
Y. Shi
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Song, NY - Differences in developmental changes in GABAergic response between bushy and stellate cells in the rat anteroventral cochlear nucleus. ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
33
species
rat
age
P5–P15
brain region
anteroventral cochlear nucleus
layer
cell
bushy and stellate cells
aspect
GABAergic inhibition and excitatory action
statement
the longer excitatory action of GABA may render stellate cells more vulnerable than bushy cells to excitotoxic substances during development.
pmid
22382210
title
Differences in developmental changes in GABAergic response between bushy and stellate cells in the rat anteroventral cochlear nucleus.
contact Name
Song, NY
contributed by
John Fielden
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer - Efficient recruitment of layer 2/3 interneurons by layer 4 input in single columns of rat somatosensory cortex. ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
34
species
rat
age
p20 - p29
brain region
somatosensory cortex
layer
L4-to-L2/3
cell
interneurons and PCs
aspect
translaminar innervation of L2/3 interneurons by spiny neurons in the main cortical input layer 4 (L4).
statement
L4 spiny neurons may more efficiently recruit L2/3 interneurons than L2/3 pyramidal neurons, and that glutamate release from translaminar boutons of L4 spiny neuron axons is target cell specific.
pmid
18701690
title
Efficient recruitment of layer 2/3 interneurons by layer 4 input in single columns of rat somatosensory cortex.
contact Name
Moritz Helmstaedter, Bert Sakmann and Dirk Feldmeyer
contributed by
Mirjia Herzog
JWG notes
No actual data concerning morphology. Has density plots.
checked by
SR

not applicable - Liao, C.C. - Evidence for structural and functional changes of subplate neurons in developing rat barrel cortex ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
35
species
rat
age
p0-14
brain region
somatosensory cortex
layer
L4
cell
subplate neurons
aspect
maturation process of SPns
statement
the reduction of neuronal excitability, synaptic transmission and dendritic complexity may attribute to the decline of functional connectivity between thalamus and subplate
pmid
22002739
title
Evidence for structural and functional changes of subplate neurons in developing rat barrel cortex
contact Name
Liao, C.C.
contributed by
John Fielden
JWG notes
Concerns subplate neurons -- not cortical.
checked by
SR

not applicable - Yasuo Kawaguchi - Groupings of nonpyramidal and pyramidal cells with specific physiological and morphological characteristics in rat frontal cortex ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
36
species
rat
age
P16-22
brain region
frontal cortex
layer
L5
cell
PC,IN
aspect
morphological characteristics
statement
The somal size of the two classes of nonpyramidal cells was similar. FS cells were all multipolar in shape, whereas LTS cells included both multipolar and bitufted types. The dendrites of some FS cells extended up into layers II/III, but there were also other FS cells with their dendrites restricted in layer V. Dendrites of LTS cells were mostly restricted to layer V. Dendrites of FS cells were mostly smooth, but those of LTS cells possessed a modest but consistent population of spines.
pmid
8459275
title
Groupings of nonpyramidal and pyramidal cells with specific physiological and morphological characteristics in rat frontal cortex
contact Name
Yasuo Kawaguchi
contributed by
Y. Shi
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Liguz-Lecznar, M. - Impairment of experience-dependent cortical plasticity in aged mice ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
37
species
mouse
age
p3-24
brain region
somatosensory cortex
layer
2,4
cell
all
aspect
relationship between aging and experience-dependent plasticity
statement
In the barrel cortex, distinct forms of experience-dependent plasticity are differentially affected by the aging process.
pmid
20005597
title
Impairment of experience-dependent cortical plasticity in aged mice
contact Name
Liguz-Lecznar, M.
contributed by
John Fielden
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Zhong-Wei Zhang and Martin Deschenes - Intracortical Axonal Projections of Lamina VI cells of the Primary Somatosensory Cortex in the Rat: A single-Cell Labelling Study ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
38
species
rat
age
brain region
somatosensory cortex
layer
Layer VI
cell
aspect
Relationships between morphology arborization and network
statement
Dendritic morphology and axonal arborizations of corticothalamic cells relate to the projection target
pmid
9236245
title
Intracortical Axonal Projections of Lamina VI cells of the Primary Somatosensory Cortex in the Rat: A single-Cell Labelling Study
contact Name
Zhong-Wei Zhang and Martin Deschenes
contributed by
Guy Atenekeng
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Monika Jadi - Location-Dependent Effects of Inhibition on Local Spiking in Pyramidal Neuron Dendrites ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
39
species
rat
age
P20-40
brain region
somatosensory cortex
layer
5
cell
interneurons and PCs
aspect
inhibitory input site
statement
Effects of inhibitory input location on Pc integration
pmid
22719240
title
Location-Dependent Effects of Inhibition on Local Spiking in Pyramidal Neuron Dendrites
contact Name
Monika Jadi
contributed by
Rodrigo Perin
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Harry B M Uylings1,2,3 and Jaap van Pelt1 - Measures for quantifying dendritic arborizations ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
40
species
rat
age
brain region
layer
cell
all
aspect
different measurements of dendritic morphology
statement
Exhaustive list of different measurements for dendritic morphology
pmid
12222821
title
Measures for quantifying dendritic arborizations
contact Name
Harry B M Uylings1,2,3 and Jaap van Pelt1
contributed by
Yihwa Kim
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Diamond, Marian C. - Morphological changes in the young, adult and aging rat cerebral cortex, hippocampus, and diencephalon ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
41
species
rat
age
young, adult
brain region
cerebral cortex,hippocampus,diencephalon
layer
cell
aspect
Morphological changes
statement
 In general, the depth of all the forebrain structures increases to 26 days of age at which time the cerebral cortex decreases while the hippocampus and diencephalon continue to increase until 650 days of age.
pmid
1137540
title
Morphological changes in the young, adult and aging rat cerebral cortex, hippocampus, and diencephalon
contact Name
Diamond, Marian C.
contributed by
Y. Shi
JWG notes
Article unavailable online
checked by
SR

not applicable - J.I. Arellano, A. Espinosa, J. DeFelipe - non - synaptic dendritic spines in neocortex ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
42
species
mouse
age
2-3 months
brain region
cortex
layer
cell
aspect
dendritic spines without synapses
statement
3.6 % of the spines lacked synapses, nonsynaptic spines were small and had no clear head
pmid
17240073
title
non - synaptic dendritic spines in neocortex
contact Name
J.I. Arellano, A. Espinosa, J. DeFelipe
contributed by
Sarah Strauss
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Zaitsev A V - P/Q-type, but not N-type, calcium channels mediate GABA release from fast-spiking interneurons to pyramidal cells in rat prefrontal cortex . ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
43
species
rat
age
p19-p22
brain region
medial prefrontal cortex
layer
2,3
cell
fast spiking interneurons
aspect
dendrite
statement
multipolar aspiny dendrites
pmid
17329622
title
P/Q-type, but not N-type, calcium channels mediate GABA release from fast-spiking interneurons to pyramidal cells in rat prefrontal cortex .
contact Name
Zaitsev A V
contributed by
Monica Favre
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Zaitsev A V - P/Q-type, but not N-type, calcium channels mediate GABA release from fast-spiking interneurons to pyramidal cells in rat prefrontal cortex . ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
44
species
rat
age
p19-p22
brain region
medial prefrontal cortex
layer
2,3
cell
fast spiking interneurons
aspect
axon arbor
statement
relatively uniformly or predominantly horizontally spread axon arbors
pmid
17329622
title
P/Q-type, but not N-type, calcium channels mediate GABA release from fast-spiking interneurons to pyramidal cells in rat prefrontal cortex .
contact Name
Zaitsev A V
contributed by
Monica Favre
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - The Petilla Interneuron Nomenclature Group (PING)* - Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
45
species
age
brain region
layer
cell
aspect
a review of interneuron types (m-type as well as e-type)
statement
pmid
18568015
title
Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex
contact Name
The Petilla Interneuron Nomenclature Group (PING)*
contributed by
Yihwa Kim
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Nelson Spruston - Pyramidal neurons: dendritic structure and synaptic integration ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
46
species
rat
age
brain region
layer
Layer 5
cell
Pyramidal cell
aspect
Dendritic and synaptic
statement
The existence of dendritic domains with distinct synaptic inputs, excitability, modulation and plasticity appears to be a common feature that allow synapse throughout the dendritic tree to contribute to action potential generation
pmid
18270515
title
Pyramidal neurons: dendritic structure and synaptic integration
contact Name
Nelson Spruston
contributed by
Guy Atenekeng
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Nelson Spruston - Pyramidal neurons: dendritic structureand synaptic integration ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
47
species
review
age
review
brain region
neocortex and CA1
layer
L2/3 and L5
cell
PC
aspect
Dendritic properties in compared PC
statement
Review on dendritic properties across different kinds of PC
pmid
18270515
title
Pyramidal neurons: dendritic structureand synaptic integration
contact Name
Nelson Spruston
contributed by
MPG
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Giorgio A. Ascoli, - Quantitative Morphometry of hippocampal pyramidal cells: differences between anatomical classes and reconstructing laboratories. ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
48
species
rat
age
p2-24
brain region
layer
cell
Pyramidal cell
aspect
Morphologies classification
statement
Large number of parameter found that discriminated among neurons within the same morphological, but reconstructed in different laboratories
pmid
15101088
title
Quantitative Morphometry of hippocampal pyramidal cells: differences between anatomical classes and reconstructing laboratories.
contact Name
Giorgio A. Ascoli,
contributed by
Guy Atenekeng
JWG notes
Has data, but from hippocampal pyramidal cells
checked by
SR

not applicable - J Deuchars, D C West and A M Thomson - Relationships between morphology and physiology of pyramid-pyramid single axon connections in rat neocortex in vitro ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
49
species
rats (male)
age
120-180g (~p24-30)
brain region
rat somatomotor cortex
layer
layer V-VI
cell
pyramidal
aspect
Relationships between morphology and physiology of pyramid-pyramid single axon connections
statement
first illustration of a morphological basis for variations in functional properties of pyramid-pyramid connections in the neocortex.
pmid
7965856
title
Relationships between morphology and physiology of pyramid-pyramid single axon connections in rat neocortex in vitro
contact Name
J Deuchars, D C West and A M Thomson
contributed by
Dimitri Christodoulou
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Christie, J.M. & Jahr, C.E. - Selective Expression of Ligand-Gated Ion Channels in L5 Pyramidal Cell Axons ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
50
species
rat
age
p13-19
brain region
Visual cortex
layer
5
cell
PCs
aspect
ion channel expression
statement
NMDARs are excluded from the axon of L5 pyramidal cells of visual cortex
pmid
19759293
title
Selective Expression of Ligand-Gated Ion Channels in L5 Pyramidal Cell Axons
contact Name
Christie, J.M. & Jahr, C.E.
contributed by
John Fielden
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Kaiserman-abramof, I.R - The small pyramidal neuron of the rat cerebral cortex. The perikaryon, dendrites and spines. ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
51
species
rat
age
brain region
parietal cx
layer
cell
aspect
Spine Length
statement
approx 2 um
pmid
4985058
title
The small pyramidal neuron of the rat cerebral cortex. The perikaryon, dendrites and spines.
contact Name
Kaiserman-abramof, I.R
contributed by
Melissa
JWG notes
Article unavailable online
checked by
SR

not applicable - Svoboda, Karel - The subcellular organization of neocortical excitatory ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
52
species
mouse
age
p26-34
brain region
barrel cortex
layer
2,3,4,5
cell
pc
aspect
thalamic input
statement
This paper maps thalamic input to neocortex with subcellular resolution
pmid
19151697
title
The subcellular organization of neocortical excitatory
contact Name
Svoboda, Karel
contributed by
Rodrigo Perin
JWG notes
No actual data concerning morphology.
checked by
SR

not applicable - Gyorgy Buzsaki - Three dimensional reconstruction of the axon arbor of a CA3 pyramidal cell recorded and filled in vivo ext_link

input/validation/consistent
not applicable
evaluation criterion
not applicable
id
53
species
rat
age
brain region
CA3
layer
L2-6
cell
Pyramidal cell
aspect
Neuron reconstruction and statistics
statement
Reconstruction of collaterals axon exceeded 0.5m with almost 40000 synaptic boutons
pmid
17717699
title
Three dimensional reconstruction of the axon arbor of a CA3 pyramidal cell recorded and filled in vivo
contact Name
Gyorgy Buzsaki
contributed by
Guy Atenekeng
JWG notes
Has data, but from hippocampal pyramidal cells
checked by
SR

possibly consistent - Yasao Kawaguchi - Axon Branching and Synaptic Bouton Phenotypes in GABAergic Nonpyramidal Cell Subtypes ext_link

input/validation/consistent
possibly consistent
evaluation criterion
Axonal branching patterns of L2/3 and L5 GABAergic interneurons in mPFC
id
54
species
rat
age
P8(weeks)
brain region
layer
Layer II/III, V
cell
Non pyramidal cell
aspect
Axon Branching and GABAergic Nonpyramidal cell subtypes
statement
Non pyramidal cells have a common mechanism of axon branching and bouton arrangement
pmid
15044524
title
Axon Branching and Synaptic Bouton Phenotypes in GABAergic Nonpyramidal Cell Subtypes
contact Name
Yasao Kawaguchi
contributed by
Guy Atenekeng
JWG notes
Data!
checked by
SR

possibly consistent - Staiger JF, Masanneck C, Schleicher A, Zuschratter W. - Calbindin-containing interneurons are a target for VIP-immunoreactive synapses in rat primary somatosensory cortex. ext_link

input/validation/consistent
possibly consistent
evaluation criterion
Dendritic morphometrics of CB +ve and VIP +ve interneurons in L2/3 & L4 rat S1
id
55
species
rat
age
brain region
somatosensory neocortex
layer
layers II-VI
cell
Interneurons
aspect
output of a subpopulation of cortical interneurons which express vasoactive intestinal polypeptide (VIP)
statement
all calbindin-containing cortical interneurons seem to be under direct influence of other GABAergic interneurons expressing the peptide VIP. An indirect functional consequence of this may be disinhibition of pyramidal cells, which are considered the major target of calbindin interneurons. However, since the examined types of interneurons are intricately embedded in networks of yet different interneurons, the outcome of these multiple inhibitory interactions is likely to be less simplistic. It may be related to the timing of pyramidal cell discharge within and across layers of cortical columns.
pmid
14648678
title
Calbindin-containing interneurons are a target for VIP-immunoreactive synapses in rat primary somatosensory cortex.
contact Name
Staiger JF, Masanneck C, Schleicher A, Zuschratter W.
contributed by
Mirjia Herzog
JWG notes
Data!
checked by
SR

possibly consistent - Joachim Luebke - Columnar organization of dendrites and axons of single and synaptically coupled excitatory spiny neurons in layer 4 of the rat barrel cortex. ext_link

input/validation/consistent
possibly consistent
evaluation criterion
pending evaluation - soma, dendrite and axonal morphometrics for L4SS
id
56
species
rat
age
p12-p22
brain region
barrel cortex
layer
L4
cell
SS/SP
aspect
cortico-cortical projections
statement
SS: synaptic contacts (two to five) were distributed over the entire dendritic tree but preferentially located on tertiary dendrites and relatively close to the soma. More than 75% of all synaptic boutons were found in layers 4 and 2/3, with the highest density in layer 2/3; the remaining 25% of synaptic boutons were found in layers 5 and 6. The number of synaptic boutons per 100 μm axonal segment was significantly higher (p > 0.01) in layers 2/3 and 4 than in the other layers. SP: The total number of synaptic boutons on the axons of star pyramidal cells was significantly lower than that of spiny stellate cells; the number of boutons per 100 μm axonal segment was similar to that of spiny stellate cells.
pmid
10884314
title
Columnar organization of dendrites and axons of single and synaptically coupled excitatory spiny neurons in layer 4 of the rat barrel cortex.
contact Name
Joachim Luebke
contributed by
MR
JWG notes
checked by
SR

possibly consistent - Rafael Yuste - dendritic size of pyramidal neurons differs among mouse cortical regions ext_link

input/validation/consistent
possibly consistent
evaluation criterion
Dendritic architecture of L2/3 PCs in mouse S2
id
57
species
mouse
age
brain region
different cortical regions
layer
l 2/3
cell
pyramidal neurons
aspect
dendritic architecture
statement
different cortical areas could be built out of different neuronal cell types
pmid
16195469
title
dendritic size of pyramidal neurons differs among mouse cortical regions
contact Name
Rafael Yuste
contributed by
Sarah Strauss
JWG notes
Data!
checked by
SR

possibly consistent - Ballesteros - Yanez, R. Benavides - Piccione, J. DeFelipe - Density and morphology of dendritic spines in mouse neocortex ext_link

input/validation/consistent
possibly consistent
evaluation criterion
Sholl analysis of L2/3 PC basal dendrites in S2
id
58
species
mouse
age
brain region
motor, somatosensory, visuo temporal cortex
layer
L 3
cell
pyramidal neurons
aspect
dendritic spine morphology
statement
differences in spine dimension were detected, largest spines were found in the motor region
pmid
16457955
title
Density and morphology of dendritic spines in mouse neocortex
contact Name
Ballesteros - Yanez, R. Benavides - Piccione, J. DeFelipe
contributed by
Sarah Strauss
JWG notes
One plot of dendritic sholl analysis
checked by
SR

possibly consistent - Moritz Helmstaedter1, Bert Sakmann1 and Dirk Feldmeyer - Neuronal Correlates of Local, Lateral, and Translaminar Inhibition with Reference to Cortical Columns ext_link

input/validation/consistent
possibly consistent
evaluation criterion
Axonal projection patterns of L2/3 GABAergic interneurons
id
59
species
rat
age
p20-p29
brain region
barrel cortex
layer
L2/3, 4
cell
inhibitory neurons
aspect
classification of interneurons based on the layer specific projection
statement
laterality and verticality were used as criterion to measure the morphological property of neurons
pmid
18832335
title
Neuronal Correlates of Local, Lateral, and Translaminar Inhibition with Reference to Cortical Columns
contact Name
Moritz Helmstaedter1, Bert Sakmann1 and Dirk Feldmeyer
contributed by
Yihwa Kim
JWG notes
Axonal range data, density plots
checked by
SR

possibly consistent - Nicolas Narboux-Nême - Neurotransmitter Release at the Thalamocortical Synapse Instructs Barrel Formation But Not Axon Patterning in the Somatosensory Cortex ext_link

input/validation/consistent
possibly consistent
evaluation criterion
Sholl and branch order analysis of L4 spiny neurons
id
60
species
rat
age
p0-p7
brain region
barrel cortex
layer
L4
cell
spiny stellate cells
aspect
impact of synaptic neurotransmitter release on neural circuit development
statement
efficient synaptic release is required at thalamocortical but not at corticocortical synapses for building the whisker to barrel map and for efficient sensory function
pmid
22553025
title
Neurotransmitter Release at the Thalamocortical Synapse Instructs Barrel Formation But Not Axon Patterning in the Somatosensory Cortex
contact Name
Nicolas Narboux-Nême
contributed by
John Fielden
JWG notes
Data: mouse L4SS; sholl analysis, branch order analysis
checked by
SR

possibly consistent - Areti Tsiola - Quantitative Morphologic Classification of Layer 5 Neurons from Mouse Primary Visual Cortex ext_link

input/validation/consistent
possibly consistent
evaluation criterion
m-type classification in L5 of mouse neocortex
id
61
species
Mouse
age
brain region
Primary visual cortex
layer
Layer 5
cell
pyramidal
aspect
Morphologic classification
statement
Cluster analysis of neuronal morphologies provides an objective method to quatitatively define different neuronal phenotypes and may serve as a basis for describing neocortical circuits
pmid
12746859
title
Quantitative Morphologic Classification of Layer 5 Neurons from Mouse Primary Visual Cortex
contact Name
Areti Tsiola
contributed by
Guy Atenekeng
JWG notes
Data!
checked by
SR

possibly consistent - Veronica Egger1, Thomas Nevian2 and Randy M. Bruno - Subcolumnar Dendritic and Axonal Organization of Spiny Stellate and Star Pyramid Neurons within a Barrel in Rat Somatosensory Cortex ext_link

input/validation/consistent
possibly consistent
evaluation criterion
pending evaluation - axonal organization of L4SS and SP
id
62
species
rat
age
brain region
barrel cortex
layer
cell
aspect
morphology
statement
relating the asymmetry of neuron morphology with the location of neuron in a barrel
pmid
17656622
title
Subcolumnar Dendritic and Axonal Organization of Spiny Stellate and Star Pyramid Neurons within a Barrel in Rat Somatosensory Cortex
contact Name
Veronica Egger1, Thomas Nevian2 and Randy M. Bruno
contributed by
Yihwa Kim
JWG notes
checked by
SR

possibly consistent - Marcel Oberlaender - Three-dimensional axon morphologies of individual layer 5 neurons indicate cell type-specific intracortical pathways for whisker motion and touch ext_link

input/validation/consistent
possibly consistent
evaluation criterion
pending evaluation - laminar axonal extents of L5STPC and L5TTPC
id
63
species
rat
age
brain region
barrel cortex
layer
L5
cell
pc
aspect
projections
statement
difference in axonal projection of slender and thick tufted L5 pc neurons and also their distinct roles during the behavioral paradigm (active and passive touch)
pmid
21368112
title
Three-dimensional axon morphologies of individual layer 5 neurons indicate cell type-specific intracortical pathways for whisker motion and touch
contact Name
Marcel Oberlaender
contributed by
Yihwa Kim
JWG notes
checked by
SR